Fixed- versus Variable-RBE Computations for Intensity Modulated Proton Therapy
نویسندگان
چکیده
منابع مشابه
Intensity modulated proton therapy.
Intensity modulated proton therapy (IMPT) implies the electromagnetic spatial control of well-circumscribed "pencil beams" of protons of variable energy and intensity. Proton pencil beams take advantage of the charged-particle Bragg peak-the characteristic peak of dose at the end of range-combined with the modulation of pencil beam variables to create target-local modulations in dose that achie...
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The advanced developments in external beam radiation therapy (EBRT) over the past few decades have improved dose conformity to the target while minimizing dose to the surrounding organs at risk (OAR). Intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) are two commonly used EBRT techniques to treat cancer. In sliding window (SW) or dynamic IMRT, each radiati...
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June 01, 2008 External-beam radiation is a highly effective curative treatment option for men with localized prostate cancer.[1,2] Over the past several decades, efforts have been made to improve the “therapeutic ratio” of radiation by increasing dose to improve cure rates without causing a substantial increase in side effects. Due to its potential to create superior dose distributions, proton ...
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A high dosimetric quality and short treatment time are major goals in radiotherapy planning. Intensity modulated proton therapy (IMPT) plans obtain dose distributions of great conformity but often result in long delivery times which are typically not incorporated into the optimization process. We present an algorithm to optimize delivery efficiency of IMPT plans while maintaining plan quality, ...
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Purpose: In the current study, using different radiobiological models, tumor control probability (TCP) and normal tissue complication probability (NTCP) of radiotherapy plans were calculated for three-dimensional conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) of prostate cancer.Methods and Materials: 10 prostate plans were randomly selected among patients ...
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ژورنال
عنوان ژورنال: Advances in Radiation Oncology
سال: 2019
ISSN: 2452-1094
DOI: 10.1016/j.adro.2018.08.020